GenomicsNews.net
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- 11 Apr 2007 Agilent Technologies Inc. today introduced a microarray-based assay for microRNA (miRNA) expression profiling, delivering new levels of sensitivity and specificity while incorporating simple protocols for labeling and detection. The assay allows for very small amounts of sample (100 ng of total RNA), making it well-suited for miRNA expression profiling experiments. miRNAs, a class of small non-coding RNAs that are only 19-30 nucleotides long, are estimated to regulate approximately 30 percent of all human genes. They were little understood five years ago, but now there are approximately 500 known miRNAs in humans, with ongoing discovery directed toward an estimated 10,000. Recent studies have shown that distinct miRNA expression patterns are associated with a number of tumor types as well as involved in regulating processes such as c...
