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Mesotherapy is almost a painless injection of vitamins, amino acids, minerals, and medications placed into the mesoderm (“meso” means middle and “derm” means skin). The key to this procedure is that a doctor injects micro-doses of medication into the local problem area using a tiny needle specially manufactured for this procedure. The mesotherapy method of delivery ensures that active components penetrate deep into the skin, which does not happen when topical creams are applied.